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Spero Therapeutics, Inc.

SPRO Health Care Biotechnology: Pharmaceutical Preparations
$1.11
▼ -5.1% Today
as of Oct 23, 15:06 ET
Last 30 days -2.63% Sep 14 → Oct 23
$1.08 $1.15 $1.23 $1.31 $1.38 Sep 14 Sep 22 Sep 30 Oct 07 Oct 15 Oct 23
Open
$1.16
High
$1.17
Low
$1.13
Volume
$201,699
Avg Vol
$729,385
Mkt Cap
$73M
P/E (TTM)
—
Beta
—
52w High
$3.08
52w Low
$1.08
Div Yield
—
Shares Out
$58M

Recent Press Releases & News last 60 days · 5 items

Oct 21 · 06:02 MarketBeat
Spero Therapeutics Targets 2027 Phase II Launch for SP001 in IgG4-Related Disease
Oct 15 · 20:05 PR GlobeNewswire
Spero Therapeutics to Participate in the Chardan 10th Annual Healthcare Conference
Oct 2 · 20:05 PR GlobeNewswire
Spero Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
▸ Show all 5 press releases & news Free account →

SPRO earnings at a glance

The options market is pricing a move of about ±15.6% after the report, a range of roughly $0.94 to $1.28 from today's $1.11. Over its last 2 reports the stock rose the next day 1 time and fell 1, moving ±8.5% on average; after the most recent report on May 13, 2026 it moved -3.9%. That means options currently expect more movement than SPRO has typically delivered. SPRO beat the consensus EPS estimate in 3 of its last 3 reported quarters. Implied volatility is currently 80%. The share price of $1.11 sits near its 52-week low.

More Health Care stocks · All stocks · Earnings calendar

Overview

52-week range
$1.08
$3.08
2% of range
Avg surprise (last 3)
+64.9%
Avg reaction (last 2)
+4.6%
50% positive
Latest IV / EM
80%
EM ±15.6% · $2 · Oct 16

Earnings trends

EPS — actual vs estimate Actual Estimate
$-0.55$-0.42$-0.29$-0.16$-0.03 Actual $-0.25Actual $-0.23Actual $-0.06Actual $-0.24Actual $-0.33Actual $-0.32Actual $-0.25Est $-0.55Actual $-0.03Est $-0.38Actual $-0.13Est $-0.25Actual $-0.13Actual $-0.16 MarJunSepMarJunSepMar/2025Jun/2025Sep/2025Mar/2026Jun
Revenue vs Net Income Revenue Net income
$-17M$-9M$-1M$7M$15M Sep 24Mar 25Jun 25Sep 25Mar 26Jun 26

Earnings history

DatePeriodActual EPSEstSurpriseYoY %ΔDay reactSource
Tue Jun 30, 2026Jun 2026 $-0.16 — — — — financials
Wed May 13, 2026Mar/2026 $-0.13 — — +48.0% -3.9% earnings
Thu Nov 13, 2025Sep/2025 $-0.13 $-0.25 +48.0% — — earnings
Tue Aug 12, 2025Jun/2025 $-0.03 $-0.38 +92.1% — — earnings
Tue May 13, 2025Mar/2025 $-0.25 $-0.55 +54.5% — +13.1% earnings
Mon Sep 30, 2024Sep 2024 $-0.32 — — — — financials
Sun Jun 30, 2024Jun 2024 $-0.33 — — — — financials
Sun Mar 31, 2024Mar 2024 $-0.24 — — — — financials
Sat Sep 30, 2023Sep 2023 $-0.06 — — — — financials
Fri Jun 30, 2023Jun 2023 $-0.23 — — — — financials
Fri Mar 31, 2023Mar 2023 $-0.25 — — — — financials

Financials

Income statement (quarterly)

MetricJun 2026Mar 2026Dec 2025Sep 2025Jun 2025Mar 2025Dec 2024Sep 2024
Revenue$0$258,000—$5M$14M$6M—$13M
Cost of revenue————————
Gross profit————————
Operating income$-10M$-8M—$-8M$-2M$-15M—$-19M
Net income$-10M$-7M—$-7M$-2M$-14M—$-17M
EPS (diluted)$-0.16$-0.13—$-0.13$-0.03$-0.25—$-0.32

Balance sheet (quarterly)

MetricJun 2026Mar 2026Dec 2025Sep 2025Jun 2025Mar 2025Dec 2024Sep 2024
Cash & equivalents$51M$56M$40M$49M$31M$49M$53M$76M
Inventory————————
Total current assets$52M$58M$67M$52M$59M$75M$107M$132M
Total assets$53M$59M$69M$54M$62M$78M$111M$135M
Long-term debt————————
Total liabilities$9M$6M$10M$28M$29M$44M$64M$70M
Total equity$44M$53M$59M$26M$33M$34M$46M$66M

Implied volatility — last 90 days

79%860%1641%2421%3202% Jun 08 — IV 173% · EM ±22.8%Jun 09 — IV 181% · EM ±22.6%Jun 10 — IV 142% · EM ±16.7%Jun 11 — IV 176% · EM ±19.4%Jun 12 — IV 190% · EM ±19.4%Jun 15 — IV 297% · EM ±21.5%Jun 16 — IV 284% · EM ±16.8%Jun 17 — IV 879% · EM ±36.7%Jun 19 — IV 124% · EM ±27.4%Jun 22 — IV 157% · EM ±32.8%Jun 23 — IV 140% · EM ±28.7%Jun 24 — IV 141% · EM ±28.2%Jun 25 — IV 144% · EM ±28.2%Jun 26 — IV 200% · EM ±38.2%Jun 29 — IV 175% · EM ±31.0%Jun 30 — IV 138% · EM ±23.8%Jul 01 — IV 128% · EM ±21.4%Jul 02 — IV 172% · EM ±27.8%Jul 03 — IV 175% · EM ±27.3%Jul 06 — IV 148% · EM ±20.5%Jul 07 — IV 245% · EM ±32.4%Jul 08 — IV 221% · EM ±27.6%Jul 09 — IV 260% · EM ±30.7%Jul 10 — IV 345% · EM ±38.1%Jul 13 — IV 384% · EM ±32.1%Jul 14 — IV 1145% · EM ±82.8%Jul 15 — IV 1645% · EM ±97.1%Jul 16 — IV 3203% · EM ±133.8%Jul 20 — IV 626% · EM ±147.9%Jul 21 — IV 592% · EM ±137.7%Jul 22 — IV 688% · EM ±157.5%Jul 23 — IV 1014% · EM ±228.1%Jul 24 — IV 951% · EM ±210.1%Jul 27 — IV 978% · EM ±204.2%Jul 28 — IV 920% · EM ±188.3%Jul 29 — IV 789% · EM ±158.1%Jul 30 — IV 1106% · EM ±216.7%Jul 31 — IV 1161% · EM ±222.2%Aug 03 — IV 1178% · EM ±208.7%Sep 22 — IV 91% · EM ±18.5%Sep 23 — IV 79% · EM ±15.9%Sep 24 — IV 80% · EM ±15.6%

Sector peers

HRTX
Heron Therapeutics, Inc.
$73M $0.30-13.2%
MAIA
MAIA Biotechnology, Inc.
$73M $1.15+0.4%
LFVN
Lifevantage Corporation
$76M $5.71-4.0%
CTOR
Citius Oncology, Inc.
$71M $0.66-5.6%
CING
Cingulate Inc.
$69M $4.79+2.8%
TELO
Telomir Pharmaceuticals, Inc.
$80M $0.98-4.4%

SPRO earnings FAQ

What is SPRO's expected move for earnings?

Options currently price a move of about ±15.6%, or $0.17 per share either way from $1.11.

How does SPRO stock usually react to earnings?

Across the last 2 reports the average next-day move was ±8.5%, up 1 times and down 1 times.

What is SPRO's implied volatility?

SPRO's at-the-money implied volatility is about 80% based on the latest options snapshot.

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