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Spyre Therapeutics, Inc.

SYRE Health Care Biotechnology: Pharmaceutical Preparations
$73.65
▼ -6.2% Today
as of Jun 7, 07:28 ET
Last 30 days +7.31% Apr 28 → Jun 05
$65.67 $69.11 $72.55 $75.99 $79.43 Apr 28 May 05 May 13 May 20 May 29 Jun 05
Open
$77.77
High
$78.90
Low
$73.06
Volume
$945,809
Avg Vol
$830,016
Mkt Cap
$6.3B
P/E (TTM)
Beta
52w High
$78.90
52w Low
$13.93
Div Yield
Shares Out
$79M

Overview

52-week range
$14
$79
92% of range
Avg surprise (last 2)
-4.7%
Avg reaction (last 2)
+2.0%
100% positive
Latest IV / EM
90%
EM ±12.5% · $75 · Jun 18

Earnings trends

EPS — actual vs estimate Actual Estimate
$-0.76$9.46$19.69$29.91$40.14 Actual $40.14Actual $0.86Actual $0.72Actual $0.59Actual $1.06Actual $-0.74Est $-0.76Actual $-0.74Est $-0.66 JunSepMarJunSepMar/2025Mar/2026
Revenue vs Net Income Revenue Net income
$-69M$-55M$-40M$-26M$-12M Jun 24Sep 24Mar 25Jun 25Sep 25Mar 26

Earnings history

DatePeriodActual EPSEstSurpriseYoY %ΔDay reactSource
Tue May 5, 2026Mar/2026 $-0.74 $-0.66 -12.1% 0.0% +2.7% earnings
Thu May 8, 2025Mar/2025 $-0.74 $-0.76 +2.6% +1.2% earnings
Mon Sep 30, 2024Sep 2024 $1.06 financials
Sun Jun 30, 2024Jun 2024 $0.59 financials
Sun Mar 31, 2024Mar 2024 $0.72 financials
Sat Sep 30, 2023Sep 2023 $0.86 financials
Fri Jun 30, 2023Jun 2023 $40.14 financials

Financials

Income statement (quarterly)

MetricMar 2026Dec 2025Sep 2025Jun 2025Mar 2025Dec 2024Sep 2024Jun 2024
Revenue$0$0
Cost of revenue
Gross profit
Operating income$-46M$-57M$-42M$-54M$-55M$-44M
Net income$-69M$-11M$-37M$-45M$-69M$-39M
EPS (diluted)$-0.74$1.06$0.59

Balance sheet (quarterly)

MetricMar 2026Dec 2025Sep 2025Jun 2025Mar 2025Dec 2024Sep 2024Jun 2024
Cash & equivalents$97M$86M$65M$82M$48M$89M$72M$45M
Inventory
Total current assets$764M$778M$505M$539M$570M$608M$421M$436M
Total assets$764M$778M$505M$539M$570M$608M$421M$436M
Long-term debt
Total liabilities$93M$63M$50M$83M$87M$91M$94M$62M
Total equity$671M$715M$455M$456M$483M$518M$327M$374M

Implied volatility — last 90 days

85%87%90%92%95% Jun 07 — IV 90% · EM ±12.5%

Sector peers

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